Formulatsiooni

Formulatsiooni is the Estonian term for formulation, referring to the deliberate design of a product by combining active ingredients with a set of inactive components to achieve specific properties and performance. It encompasses both the planning stage and the final product, including the choice of ingredients, their proportions, and the processing methods used to produce the formulation.

A typical formulation consists of an active ingredient and excipients, which may include solvents, binders, fillers, emulsifiers, surfactants, stabilizers, preservatives, flavorings, colorants, and packaging components. Excipients are chosen to enhance delivery, stability, sensory attributes, shelf life, and manufacturability. Formulations can take many forms, including solutions, suspensions, emulsions, gels, creams, ointments, tablets, capsules, powders, and inhalable or topical products.

The formulation process involves selecting compatible ingredients, assessing stability and interactions, optimizing efficacy and safety, and ensuring manufacturability at scale. Quality control, regulatory compliance, and documentation are integral, with standards often guided by pharmacopeias, good manufacturing practices (GMP), and risk-based approaches such as Quality by Design (QbD) and design of experiments (DoE).

Applications span pharmaceuticals (oral, topical, injectable), cosmetics and personal care, agrochemicals, food flavorings and additives, and industrial materials. Effective formulatsiooni aims to deliver consistent performance, user safety, and economic viability while meeting regulatory and market requirements.