Dihydralazine

Dihydralazine is a pharmaceutical compound that belongs to the class of vasodilators. It is primarily used in the treatment of hypertension, a condition characterized by high blood pressure. Dihydralazine works by relaxing the smooth muscles in the walls of blood vessels, leading to their widening. This widening effect, known as vasodilation, reduces the resistance to blood flow, thereby lowering blood pressure.

The drug is typically administered orally. Its mechanism of action involves interfering with the influx of calcium ions into vascular smooth muscle cells, which is a crucial step in muscle contraction. By blocking calcium entry, dihydralazine prevents the muscles from constricting, promoting relaxation and blood pressure reduction.

Dihydralazine is often prescribed as part of a combination therapy for managing hypertension, especially in cases where monotherapy is insufficient. Its use may be associated with certain side effects, which can include headache, dizziness, nausea, and tachycardia (a rapid heart rate). Like other antihypertensive medications, its administration should be carefully monitored by a healthcare professional to ensure optimal efficacy and safety. The precise dosage and frequency of administration are determined based on individual patient needs and response.