Deglycyrrhinated

Deglycyrrhinated is an adjective used to describe licorice-derived materials from which glycyrrhizin has been substantially reduced or removed. The most common form is deglycyrrhinated licorice, often abbreviated as DGL. Glycyrrhizin is a glycoside found in licorice root that can contribute to strong sweetness as well as potential adverse effects at high intake, notably mineralocorticoid-like symptoms such as elevated blood pressure and low potassium. Deglycyrrhinated preparations aim to preserve other licorice constituents while minimizing these risks.

Deglycyrrhinated licorice is produced by processing licorice root to lower glycyrrhizin content, typically through resin-based adsorption, solvent extraction, or other purification methods. The resulting products retain various non-glycyrrhizin components, including several flavonoids and related compounds, which may contribute to anti-inflammatory or soothing properties. The exact composition can vary depending on the production method and source material.

These products are commonly marketed as mucosal soothing agents, used in dietary supplements and some over-the-counter remedies for gastrointestinal comfort or oral irritation. While deglycyrrhinated licorice reduces the risk associated with glycyrrhizin, it is not without considerations. Users should follow product guidelines and consult healthcare providers if they have hypertension, kidney issues, are pregnant, or are taking medications that could interact with licorice components.