DOTANOC
DOTANOC, or Ga-68 DOTANOC, is a radiopharmaceutical used in PET imaging to visualize somatostatin receptor–expressing tumors. It is a DOTA-conjugated somatostatin analogue radiolabeled with gallium-68, enabling high-resolution PET/CT imaging of abnormal uptake in the body.
Mechanism and scope: DOTANOC binds primarily to somatostatin receptor subtypes 2, 3, and 5 with high affinity,
Clinical use: Ga-68 DOTANOC is widely used for imaging well-differentiated neuroendocrine tumors and their metastases, aiding
Procedure and interpretation: The tracer is administered intravenously, and PET/CT imaging is typically performed about 1
Availability and safety: DOTANOC is available in centers with radiopharmacy capabilities, particularly in Europe, with growing