Chorioamnionitis
Chorioamnionitis, also known as intra-amniotic infection, is an infection of the fetal membranes—the chorion and amnion—and the amniotic fluid. It most often results from ascending bacterial infection of the lower genital tract during pregnancy or labor and is associated with placental and fetal membrane inflammation.
The condition is frequently polymicrobial. Common organisms include Group B Streptococcus and Escherichia coli, with anaerobes
Clinical presentation typically includes maternal fever and tachycardia, uterine tenderness, and foul-smelling amniotic fluid; fetal tachycardia
Treatment requires intrapartum antibiotics and delivery of the fetus if feasible. Common regimens include broad-spectrum antibiotics
Prognosis improves with prompt treatment but antenatal infection is associated with maternal sepsis, postpartum endometritis, and