ChloroMDPHP

ChloroMDPHP is a research chemical that belongs to the pyrovalerone class of psychoactive substances. It is a synthetic cathinone, structurally related to other compounds like pentedrone and MDPV. Its chemical name is 1-(4-chlorophenyl)-2-(methylamino)propan-1-one. ChloroMDPHP emerged as a designer drug, often sold online as a "research chemical" or "bath salt" and is not approved for human consumption.

The pharmacological effects of ChloroMDPHP are believed to be primarily mediated through its action as a norepinephrine-dopamine reuptake inhibitor (NDRI). This means it increases the levels of these neurotransmitters in the brain, which can lead to stimulant-like effects. Users have reported experiences such as increased energy, alertness, euphoria, and a heightened sense of well-being. However, like many potent stimulants, ChloroMDPHP can also cause adverse effects. These may include anxiety, paranoia, insomnia, increased heart rate, elevated blood pressure, and potentially more severe cardiovascular or psychiatric issues.

Due to its status as a research chemical, comprehensive scientific studies on its long-term effects, safety profile, and precise mechanisms of action in humans are limited. Its psychoactive properties and potential for abuse have led to its control in various jurisdictions. Possession, sale, and use of ChloroMDPHP are regulated or prohibited in many countries. As with other novel psychoactive substances, its unpredictable nature and lack of clinical testing make it a substance of concern for public health authorities.