Cas9niknaaminen
Cas9niknaaminen is a term that has emerged in discussions surrounding the CRISPR-Cas9 gene-editing system. It refers to the concept of using the Cas9 enzyme, a key component of CRISPR, to deliberately and precisely "nick" DNA. This nicking action is distinct from the more widely known gene-cutting activity of Cas9, which typically involves creating a double-strand break in the DNA molecule.
In the context of gene editing, a single-strand nick can be a valuable tool. It allows for
Researchers have engineered variants of Cas9 that are specifically designed to perform nicking rather than full