CH3CH2ONa

CH3CH2ONa, commonly known as sodium ethoxide, is an inorganic compound with the chemical formula CH3CH2ONa. It is a strong organic base and a white, hygroscopic solid that is highly reactive with water. Sodium ethoxide is typically prepared by reacting sodium metal with absolute ethanol (CH3CH2OH) in an anhydrous environment, as it readily absorbs moisture from the air.

This compound is primarily used as a catalyst in various organic synthesis reactions, particularly in the form of its solution in ethanol, known as sodium ethoxide solution. One of its most notable applications is in the synthesis of esters through the transesterification process, as well as in the production of certain pharmaceuticals and agrochemicals. It also serves as a base in the deprotonation of alcohols and carboxylic acids, facilitating subsequent reactions.

Sodium ethoxide is highly reactive and can cause severe skin and eye irritation upon contact. It is corrosive and may release toxic fumes when exposed to acids or water. Proper handling, including the use of protective equipment such as gloves, goggles, and lab coats, is essential when working with this compound. In case of accidental exposure, immediate medical attention should be sought.

Due to its strong basicity, sodium ethoxide is often used in conjunction with other reagents in organic synthesis to facilitate reactions that require highly basic conditions. It is also employed in the preparation of certain polymers and as a reagent in the Claisen condensation, a key reaction in the synthesis of β-keto esters. While it is a versatile reagent in organic chemistry, its reactivity and corrosive nature necessitate careful handling and storage in a dry, inert atmosphere to prevent degradation.