CDR2L
CDR2L, short for cerebellar degeneration-related protein 2-like, is a protein encoded by the human CDR2L gene. It belongs to the cerebellar degeneration-related (CDR) family and is related to CDR2, sharing sequence similarity and a role in neuronal and tumor-associated contexts. The exact biological function of CDR2L is not fully established, but it is considered to participate in regulatory processes within neurons and to be involved in antigenic networks linked to autoimmunity.
Expression of CDR2L is observed in neural tissue, particularly in regions such as the cerebellum, and it
Clinical relevance of CDR2L centers on its role as an autoantigen targeted by anti-Yo antibodies, which are
In research and clinical practice, assays detecting Yo antibodies or CDR2/CDR2L-specific immune responses aid in diagnosis