CB2Expression
CB2Expression refers to the expression levels of the cannabinoid receptor type 2 (CB2) gene (CNR2) in various cell types and tissues. The CB2 receptor is a G protein-coupled receptor primarily expressed in immune cells such as B cells, T cells, macrophages, microglia, and in certain non‑immune tissues including the spleen, thymus, bone marrow, and gastrointestinal tract. CB2Expression studies measure the abundance of CB2 mRNA or protein using techniques such as quantitative PCR, in situ hybridization, western blotting, flow cytometry, or immunohistochemistry. These studies provide insight into the physiological roles of CB2, which include modulation of inflammation, immune regulation, pain perception, and cellular proliferation.
In the immune system, high CB2Expression is observed in activated lymphocytes and in cells of the innate
Research into CB2Expression has implications for drug development. Selective CB2 agonists are investigated as therapeutic agents