Biofilmin
Biofilmin is a term used in microbiology to denote a proposed extracellular matrix protein that mediates cohesion within microbial biofilms. The concept is used to describe a core component of the biofilm matrix, together with polysaccharides, extracellular DNA, and other proteins. In models that include Biofilmin, it is thought to promote cell–cell adhesion and attachment to surfaces, contributing to microcolony formation and structural stability of the biofilm.
Structure and mechanism: Biofilmin is described as a secreted, surface-associated glycoprotein with affinity for polysaccharides and
Distribution and regulation: Some studies propose that Biofilmin expression is regulated by quorum sensing and environmental
Role in biofilm biology: By contributing to adhesion, maturation, and resistance to shear forces and antimicrobials,
Research status and applications: Because Biofilmin remains a debated or illustrative concept rather than a widely
See also: biofilm, extracellular polymeric substances, quorum sensing, antimicrobial resistance, biofilm disruption.