Bassorin

Bassorin is a water-insoluble gel-forming polysaccharide isolated from the seeds of Plantago species, most commonly Plantago ovata (psyllium). It constitutes the gel-forming fraction of psyllium mucilage, the other being the water-soluble psyllin. When exposed to water, bassorin swells and forms a viscous gel that increases the water content and bulk of the intestinal contents. The gel formation helps facilitate peristalsis and bowel movement.

Bassorin is not absorbed in the gastrointestinal tract; it resists enzymatic digestion and is partially fermented by colonic bacteria to short-chain fatty acids. It is widely used as a bulk-forming laxative and as a dietary fiber supplement for constipation and to help regulate stool form in diarrhea. Psyllium husk products containing bassorin and psyllin are commonly marketed for these purposes.

In medical use, bassorin-containing preparations are valued for their low systemic absorption and relatively mild side effects, though bloating, gas, and rare allergic reactions may occur. Adequate fluid intake is essential to prevent esophageal or intestinal obstruction, especially in people with swallowing disorders or motility problems.

Historically, the mucilaginous components of Plantago seeds have been employed in traditional medicine and later in pharmacognosy as laxatives and stabilizers. In modern pharmacology, the emphasis is on psyllium husk as a fiber supplement, with bassorin cited as the gel-forming fraction contributing to the laxative mechanism.