BODIPY
BODIPY refers to a class of fluorescent dyes based on the boron-dipyrromethene core. The core consists of a dipyrromethene fragment chelated by a boron atom coordinated to two fluoride ligands, forming a rigid, planar chromophore that can be functionalized at the meso position and at the 1,3,5-positions on the pyrrole rings. This modular structure supports extensive chemical modification while maintaining a bright, stable fluorescence.
Optical properties of BODIPY dyes are characterized by strong absorption in the visible region and bright
Synthesis typically involves forming a dipyrromethene intermediate from pyrrole building blocks, followed by complexation with boron
Applications of BODIPY dyes are widespread in chemistry and biology due to their brightness and versatility.
Derivatives and variants allow extensive functionalization for conjugation to biomolecules, polymers, or targeting moieties, supporting a