BMCdomain
BMCdomain, short for Bacterial Microcompartment domain, is a conserved protein domain found in a subset of bacterial shell proteins that assemble into bacterial microcompartments (BMCs). These compartments encapsulate specific metabolic pathways, enabling confinement of reactive intermediates and enhanced metabolic efficiency. The BMCdomain is commonly associated with shell components of systems such as the propanediol utilization (Pdu) and ethanolamine utilization (Eut) operons.
Structural and functional characteristics are typical of small, modular domains. The BMCdomain is generally a compact
Genomic context and diversity are notable features. BMCdomain proteins are encoded within operons alongside encapsulated enzymes,
Research and applications. Structural biology studies, including X-ray crystallography and cryo-electron microscopy, have revealed how BMCdomain-containing