BLI

BLI is an acronym that can refer to several unrelated concepts across different domains. There is no single universally recognized definition, and the intended meaning is usually determined by context.

Bio-Layer Interferometry (BLI) is a widely used technology in biophysics and biochemistry for label-free, real-time analysis of biomolecular interactions. The method uses optical biosensors with immobilized binding surfaces; as molecules bind, the interference pattern of light reflected from the sensor surface shifts, producing data on binding kinetics and affinity. BLI instruments are used in drug discovery, antibody characterization, and quality control of biotherapeutics, and are marketed by specialized vendors. This meaning is common in pharmaceutical research and life sciences laboratories.

BLI also designates the IATA airport code for Bellingham International Airport in Bellingham, Washington, United States. The code appears in airline schedules, luggage tags, and travel itineraries, and identifies the airport in transportation and logistics contexts.

In other contexts, BLI can be an acronym adopted by various organizations, research initiatives, or technology projects. The exact meaning is field-dependent, and readers should rely on accompanying terms or references to identify the intended expansion. Given the range of possible definitions, disambiguation is often necessary when encountering the acronym in written text or data.