Anomerization
Anomerization is the interconversion between the alpha (α) and beta (β) anomers of a cyclic carbohydrate, occurring at the anomeric carbon of hemiacetals or hemiketals. In solution, this process is commonly referred to as mutarotation for aldoses.
The interconversion typically proceeds through ring opening to the open-chain form, which contains a carbonyl group.
Acid- or base-catalyzed conditions can accelerate anomerization. The rate of mutarotation is influenced by factors such
The phenomenon has practical implications for the physical properties, reactivity, and biological recognition of sugars. Optical