ACBD
ACBD stands for acyl-CoA binding domain-containing proteins, a family of eukaryotic proteins defined by a conserved acyl-CoA binding domain capable of binding fatty acyl-CoA esters. Members vary in size and subcellular localization, with some soluble in the cytosol and others anchored to membranes or organelles. The binding site suggests roles in lipid metabolism, transport, and signaling, but the exact functions are diverse and context-dependent across the family.
Key members include ACBD3, ACBD4, and ACBD5. ACBD3 is a Golgi-associated protein involved in organizing Golgi
Beyond these, other ACBD family members exist with tissue-specific expression and varied localizations, contributing to lipid
Clinical relevance is primarily active in research contexts. Disruptions or altered expression of ACBD genes have