A00

A00 is the ICD-10 code for cholera, a severe diarrheal disease caused by infection with the bacterium Vibrio cholerae. In the ICD-10 classification, cholera is grouped under the A00 category, with subcodes A00.0, A00.1, and A00.9 detailing specific etiologies: A00.0 cholera due to Vibrio cholerae 01, biovar cholerae; A00.1 cholera due to Vibrio cholerae 01, biovar eltor; A00.9 cholera, unspecified. This places cholera at the start of the A00–A09 block, which covers intestinal infectious diseases.

Cholera is transmitted primarily through ingestion of water or food contaminated with V. cholerae, often in regions with inadequate water treatment, sanitation, and hygiene. It can cause abrupt onset of profuse, watery diarrhea and vomiting, leading to rapid dehydration and electrolyte imbalances; severe cases may progress to hypovolemic shock and death if not treated promptly.

Diagnosis is usually clinical during outbreaks and is supported by laboratory testing, such as stool culture or rapid tests to identify V. cholerae. Treatment centers on rapid rehydration, using oral rehydration solutions or intravenous fluids for severe dehydration, along with electrolyte replenishment. Antibiotics may reduce the duration and volume of stool loss in severe cases. Vaccination against cholera exists and is deployed in outbreak settings or for travelers to high-risk areas, though it does not replace the need for clean water and proper sanitation.

International health authorities monitor cholera for public health surveillance, and the A00 code provides a standardized reference for coding, data collection, and reporting within medical records.