2phenylethan1amine

2-phenylethan-1-amine, commonly known as phenethylamine (PEA), is a simple primary amine with the chemical formula C8H11N. Its structure consists of a benzene ring attached to a two-carbon chain ending in an amino group, making it a member of the class of monoamine alkylamines. As a weak base, it forms salts such as phenethylamine hydrochloride, which are often more practical for handling and storage.

Phenethylamine occurs in trace amounts in various foods and human tissues. In humans, it is produced in small quantities by the decarboxylation of phenylalanine and is rapidly metabolized by monoamine oxidases, giving it a short biological half-life and limiting sustained central effects. It is considered a trace amine with potential neuromodulatory roles, and its endogenous levels can be influenced by physiology and diet.

In addition to its endogenous presence, phenethylamine serves as a chemical building block in medicinal chemistry. It forms the core scaffold for many substituted phenethylamines, including compounds studied as pharmaceuticals and psychoactive agents. Because of its basic amine functionality, phenethylamine participates in various synthesis pathways, but detailed synthesis methods are beyond the scope of general discussion.

Safety and handling considerations align with those for handling simple amines: phenethylamine can be irritating to skin and eyes and should be used with appropriate protective equipment and in well-ventilated settings. It is not typically encountered as a consumer compound outside of research or industrial contexts.