17ketone
17-ketosteroids, often abbreviated as 17-KS, are a group of steroid hormones characterized by a ketone group at the 17th carbon position. These compounds are primarily metabolites of androgens, such as testosterone and androstenedione, and adrenal androgens, like dehydroepiandrosterone (DHEA). Their presence in the body is an indicator of adrenal and gonadal steroid production.
The major 17-ketosteroids found in urine include dehydroepiandrosterone sulfate (DHEA-S), androsterone, and etiocholanolone. DHEA-S is the
Measurement of urinary 17-ketosteroids has historically been used as a diagnostic tool to assess androgen production