trifluorinated
Trifluorinated refers to a molecule or functional group that contains three fluorine atoms. The presence and position of these fluorine atoms can significantly alter the chemical and physical properties of the parent compound. Fluorine is the most electronegative element, and its introduction into a molecule often leads to increased stability, altered solubility, and modified reactivity. For instance, trifluorinated methyl groups (-CF3) are electron-withdrawing and can affect the acidity or basicity of nearby functional groups.
Trifluorinated compounds find applications in various fields. In pharmaceuticals, the trifluorinated moiety can improve a drug's