transporterom
Transporterom is a term used in molecular and systems biology to describe the complete set and interaction network of transporter proteins that move substrates across biological membranes. It encompasses proteins that import nutrients, export waste, and regulate ion and metabolite flux, including membrane transporters such as solute carrier (SLC) family members, ATP-binding cassette (ABC) transporters, exchangers, pumps, and vesicular transport proteins. The transporterom can refer to the transporter gene repertoire encoded in a genome (the transporterome) or the expressed and functional network within a given cell type or tissue, incorporating expression levels, protein localization, and regulatory interactions.
Defining a transporterom involves integrating multi-omics data to capture potential capabilities, actual abundance, regulation, and localization.
Limitations include tissue specificity, dynamic regulation, redundancy, and incomplete functional annotation. The term remains a conceptual