transketolas
Transketolas is not a standard term in modern biochemistry and is rarely used in primary references. It is sometimes used informally to refer to transketolases, a group of enzymes that catalyze two-carbon transfer reactions in the pentose phosphate pathway. In most literature, the core enzymes are called transketolase (TKT) and transketolase-like proteins (such as TKTL1 and TKTL2).
Transketolases catalyze the transfer of a two-carbon unit from a ketose donor to an aldose acceptor. They
Functionally, transketolases help rearrange carbon skeletons to balance the PPP, generating ribose-5-phosphate for nucleotide synthesis and
Distribution and variants: in humans, the primary enzyme is transketolase (TKT); related proteins such as TKTL1
Clinical relevance: thiamine (vitamin B1) status affects transketolase activity, and erythrocyte transketolase activity measurements are used