tranexilic

Tranexamic acid is a synthetic amino acid derivative that acts as an antifibrinolytic agent. It works by competitively inhibiting the activation of plasminogen to plasmin, an enzyme that breaks down fibrin clots. By preventing clot breakdown, tranexamic acid helps to stabilize blood clots and reduce bleeding. It is administered intravenously or orally.

Medically, tranexamic acid is used to treat or prevent excessive blood loss in various situations. It is commonly employed in surgery, particularly during orthopedic procedures, cardiac surgery, and liver transplants, to reduce the need for blood transfusions. It is also used for heavy menstrual bleeding (menorrhagia), nosebleeds, and bleeding associated with certain medical conditions like hereditary angioedema. In some instances, it is used to manage bleeding from trauma or gastrointestinal sources.

The effectiveness of tranexamic acid can vary depending on the underlying cause and severity of bleeding. While generally well-tolerated, potential side effects can include gastrointestinal upset, dizziness, and visual disturbances. In rare cases, more serious adverse effects such as blood clots (thrombosis) have been reported, particularly in individuals with pre-existing risk factors. Its use requires careful consideration of the benefits versus risks by a qualified healthcare professional.