t1114q13q32
t1114q13q32 is commonly understood in genetics as a misformatted representation of the chromosomal translocation t(11;14)(q13;q32). In standard cytogenetic notation, this translocation denotes a reciprocal exchange between chromosome 11 at band q13 and chromosome 14 at band q32. The human notation t(11;14)(q13;q32) is most famously associated with mantle cell lymphoma, a B-cell neoplasm.
Molecularly, the translocation places the CCND1 gene on chromosome 11 under the control of the immunoglobulin
Clinical significance centers on its role as a diagnostic hallmark. The presence of t(11;14)(q13;q32) supports a
Detection methods include conventional karyotyping, which can reveal the translocation, and more sensitive approaches such as