sulfination
Sulfination is a broad term for chemical processes that introduce a sulfinate group into a molecule or generate sulfinate species. The sulfinate functionality encompasses the sulfinyl-sulfonyl motif, typically described as the sulfinate anion R–SO2− in salts or the related esters R–SO2–OR′. Sulfinates arise from sulfinic acids (R–SO2H) and serve as versatile intermediates in organic synthesis.
In practice, sulfination methods aim to install the SO2R group or convert substrates into sulfinate esters
Common strategies for sulfination include: (1) nucleophilic sulfination, where a sulfinate salt reacts with electrophiles such
Applications of sulfination chemistry include the preparation of sulfinates for cross-coupling and other C–S bond-forming processes,