sukusoluploidian

Sukusoluploidian is a hypothetical genomic state used in speculative biology to describe a ploidy pattern in which cells within a single organism exhibit a mosaic of different chromosome copy numbers, resulting from alternating cycles of genome duplication (polyploidization) and selective chromosomal loss or segmentation. The term is not established in mainstream cytogenetics and has no confirmed empirical evidence in natural populations.

Mechanism and features: In conceptual models, sukusoluploidian arises when development or regeneration cycles include endoreduplication events that double the genome, followed by mitotic divisions with incomplete chromosome segregation, producing daughter cells with varying ploidy. This leads to tissue mosaics where some cells are haploid, diploid, triploid, or higher, coexisting within the same tissue. Regulation would require tight control of cell-cycle checkpoints and DNA repair to mitigate instability. In theory, the pattern could be tissue- or lineage-specific and transient or more stable across development.

Occurrence and discussion: Because it is a hypothetical construct, there are no confirmed natural examples in humans or most model organisms. It is discussed in speculative biology, science education, and thought experiments to explore the boundaries of polyploidy and mosaicism.

Implications and critique: If realizable, sukusoluploidian could illuminate how organisms tolerate and regulate wide ploidy variation, influence gene dosage, and modulate cellular behavior. Critics note definitional ambiguity, potential instability, and the lack of concrete diagnostic criteria.

See also: polyploidy, endoreduplication, aneuploidy, mosaicism, genome instability.