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Sigmas is a term used across multiple disciplines to refer to the Greek letter sigma and to concepts, items, or designations that carry the sigma symbol. Sigma is the 18th letter of the Greek alphabet and appears in both its uppercase form (Σ) and lowercase forms (σ, ς). In many fields, sigma serves as a generic symbol for a range of quantities and ideas.

In mathematics and related sciences, sigma is widely used as a symbol for the summation operator (∑). In statistics, lowercase sigma denotes the standard deviation of a population, while s represents the sample standard deviation. In probability and measure theory, sigma denotes sigma-algebras, which are collections of sets closed under certain operations. In physics and engineering, sigma commonly denotes stress in a material (σ), surface charge density, or chemical sigma bonds in molecular structures.

In industry and quality management, Six Sigma refers to a data-driven methodology aimed at reducing defects and improving process capability. The term sigma level measures process performance in relation to defect rates, with higher sigma levels indicating fewer defects.

In biology, sigma factors are proteins that direct RNA polymerase to specific sets of genes, playing a key role in transcription initiation and regulation in bacteria.

In astronomy, sigmas appear as designations for stars within a constellation, where a star labeled with a Greek letter sigma (such as Sigma Geminorum) is part of a traditional naming sequence. The plural Sigmas thus encompasses various uses of the sigma symbol across science, industry, and culture.