secoisolariciresinoliin
Secoisolariciresinol is a lignan, a type of plant-derived polyphenol, classified as a phytoestrogen due to its ability to interact with estrogen receptors. It is most abundantly found in flaxseed, where the predominant lignan form is secoisolariciresinol diglucoside (SDG). In flaxseed and other plant sources, SDG occurs as a glycoside and is hydrolyzed during digestion to the aglycone secoisolariciresinol.
In the human body, gut microbiota metabolize secoisolariciresinol to the mammalian lignans enterodiol and enterolactone. These
Research on secoisolariciresinol covers possible health effects, including modulation of estrogen signaling, cardiovascular impact, and cancer
Chemically, secoisolariciresinol belongs to the class of lignans with a dibenzylbutane-type skeleton. It is commonly studied