sartan
Sartans, also known as angiotensin II receptor blockers (ARBs), are a class of medications that selectively antagonize the angiotensin II type 1 (AT1) receptor. By blocking this receptor, they prevent angiotensin II–mediated vasoconstriction and aldosterone release, leading to reduced blood pressure and improved cardiovascular and renal function in various conditions.
They are primarily used to treat hypertension and are also indicated for heart failure with reduced ejection
Common examples include losartan, valsartan, candesartan, irbesartan, olmesartan, telmisartan, and eprosartan. Losartan is a prodrug; its
Adverse effects are generally well tolerated. Potential risks include hyperkalemia, hypotension, and changes in renal function,
Developed in the late 20th century to provide alternatives to ACE inhibitors, the ARB class has become