rs90

rs90 refers to a specific single nucleotide polymorphism (SNP) found in the human genome. SNPs are common variations in DNA sequence that occur at a specific position. rs90 is located within the gene known as G6PC2, which encodes for the liver and kidney isozyme of glucose-6-phosphatase. This enzyme plays a crucial role in the regulation of blood glucose levels by catalyzing the final step of gluconeogenesis and glycogenolysis.

Research has investigated the potential association of rs90 with various metabolic traits. Studies have explored its link to fasting glucose levels, insulin sensitivity, and the risk of developing type 2 diabetes. Some findings suggest a correlation between certain genotypes at rs90 and altered glucose metabolism. However, the exact mechanisms by which rs90 influences these phenotypes are still under investigation. It is important to note that genetic associations do not imply causality, and the impact of any single SNP is often part of a complex interplay with other genetic and environmental factors. Further research is ongoing to fully elucidate the functional significance and clinical implications of rs90.