radiationsensitivity
Radiation sensitivity refers to the relative susceptibility of cells, tissues, or organisms to damage from ionizing radiation. It influences the likelihood of cell death, tissue injury, mutagenesis, and cancer risk following exposure. Sensitivity varies among cell types and conditions and is shaped by intrinsic factors and the environment.
Determinants include DNA repair capacity, cell-cycle stage, and oxygenation. Cells with efficient DNA repair, or those
Radiation sensitivity is commonly quantified with survival curves from clonogenic assays and described by radiobiological models
In practice, tissue and individual sensitivity reflect a complex mix of genetic, cellular, and microenvironmental factors.