pre40S
pre40S refers to immature particles of the small ribosomal subunit (40S) formed during ribosome biogenesis in eukaryotic cells. These pre40S particles are assembly intermediates that typically harbor the 20S pre-rRNA together with ribosomal proteins and a set of assembly factors. They are produced in the nucleolus and nucleus and are exported to the cytoplasm for final maturation into functional 40S subunits.
During ribosome biogenesis, transcription of ribosomal RNA yields precursors that are processed and assembled into pre40S
The proper formation and maturation of pre40S particles are essential for the accuracy of translation and