polyneuropatiaa
Polyneuropatiaa is a disorder characterized by damage to multiple peripheral nerves, usually in a symmetric, distal-predominant pattern. It can be acutely or chronically progressive and may affect sensory, motor, and autonomic fibers.
Common causes include diabetes mellitus, nutritional deficiencies (notably vitamin B12), chronic alcohol use, toxins (such as
Pathophysiology may involve axonal degeneration, demyelination, or both. The process is often length-dependent, with symptoms starting
Clinical features include numbness, tingling, or burning pain (sensory) and weakness with decreased reflexes (motor); autonomic
Diagnosis relies on history and examination, supported by nerve conduction studies and electromyography to distinguish axonal
Management targets the underlying cause when possible and may include optimized glucose control, nutritional supplementation, cessation