peroxiredoxinsystemen
Peroxiredoxinsystemen, commonly known as peroxiredoxins (Prx), are a family of highly conserved cysteine-based antioxidant enzymes found in all organisms from bacteria to humans. Their primary function is to reduce a variety of reactive oxygen species (ROS), such as hydrogen peroxide and organic hydroperoxides, thus protecting cells from oxidative damage. This protective role is crucial for maintaining cellular homeostasis and preventing the development of various diseases linked to oxidative stress, including cancer, neurodegenerative disorders, and aging.
The catalytic mechanism of peroxiredoxins involves a specific cysteine residue in their active site. This cysteine
Beyond their direct antioxidant activity, peroxiredoxins are increasingly recognized for their involvement in various cellular signaling