pathwayrelated

Pathwayrelated is a descriptive label used in biology and bioinformatics to denote entities, data, or analyses that are associated with biological pathways, such as metabolic or signaling cascades. The term is informal and its meaning depends on the context.

In gene expression studies, pathwayrelated commonly refers to genes annotated to a pathway, while in metabolomics it refers to metabolites and reactions that participate in a known pathway. Pathwayrelated data are often linked to standard pathway definitions in public resources.

Pathway definitions are provided by resources such as KEGG, Reactome, BioCyc, and WikiPathways, and pathwayrelated tagging supports pathway-centric analyses, including gene set enrichment analysis, pathway enrichment, and pathway-based network reconstruction.

Applications include pathway-informed feature selection in machine learning, multi-omics integration, and interpretation of results through a pathway lens. The approach can improve biological interpretability but may be biased toward well-characterized or extensively studied pathways.

Because pathwayrelated is not a formal term in major ontologies, its usage is pragmatic and varies by database or study. Users should verify the specific pathway definitions and versioning employed when interpreting pathwayrelated results.