parathormonszint

Parathormone (PTH) is a peptide hormone produced by the chief cells of the parathyroid glands. Its primary function is to regulate calcium levels in the blood. When blood calcium levels are low, the parathyroid glands release PTH, which acts on the bones, kidneys, and intestines to increase calcium levels. PTH stimulates the breakdown of bone tissue, releasing calcium into the bloodstream. It also promotes calcium reabsorption in the kidneys and enhances calcium absorption in the intestines. Conversely, when blood calcium levels are high, PTH secretion decreases, allowing calcium levels to return to normal.

Parathormone levels are typically measured to diagnose and monitor conditions related to calcium metabolism, such as hyperparathyroidism, hypoparathyroidism, and vitamin D deficiency. Hyperparathyroidism is characterized by elevated PTH levels and can lead to hypercalcemia, while hypoparathyroidism is associated with low PTH levels and hypocalcemia. Vitamin D deficiency can also result in low PTH levels due to the reduced ability of the kidneys to produce active vitamin D.

Parathormone levels are measured using a blood test, typically an intact PTH (iPTH) assay. The reference range for iPTH varies slightly among laboratories but generally falls between 15 and 65 pg/mL. Abnormal PTH levels may indicate the need for further evaluation and potential treatment, depending on the underlying condition.