pROM

PROM is an acronym that can refer to several concepts in different fields. The most common are programmable read-only memory, a type of non-volatile storage in electronics, and premature rupture of membranes, a pregnancy-related obstetric complication.

In computing, programmable read-only memory (PROM) refers to memory that is written once by an external programmer and then retained without power. Traditional PROM is one-time programmable; variations include EPROM, which can be erased with ultraviolet light, and electrically erasable PROM variants that can be erased electronically. PROM devices store firmware or bootstrap code and are chosen for low cost and non-volatility, but are not re-writable in normal use.

In obstetrics, premature rupture of membranes describes rupture of the amniotic sac before or during labor. PROM at term is distinguished from preterm PROM (PPROM). Risk factors include infection, prior PROM, multiple gestations, polyhydramnios, and smoking. Diagnosis relies on history and clinical signs such as pooling of fluid, and on tests like nitrazine and the fern test. Management depends on gestational age and infection risk and may include antibiotics, steroids for fetal lung maturity if preterm, and careful maternal–fetal monitoring.