onsetavirus

Onsetavirus is a genus of viruses within the family Coronaviridae. These viruses are characterized by their spiked surface, giving them a crown-like appearance under an electron microscope. Onsetonaviruses are known to infect a variety of mammals, including bats and rodents, and some species can also infect humans. The genus was first described in 2019, and research into its members is ongoing.

Members of the onsetavirus genus typically have a single-stranded, positive-sense RNA genome. This RNA genome encodes the virus's structural proteins, including the spike protein responsible for cell entry, and non-structural proteins involved in viral replication. The transmission routes for onsetonaviruses can vary, but often involve direct contact with infected animals or their bodily fluids, and in some cases, aerosolized particles.

The clinical manifestations of onsetavirus infections in humans can range from asymptomatic or mild respiratory illness to more severe diseases. Symptoms may include fever, cough, and shortness of breath. Diagnosis is usually confirmed through molecular testing of respiratory samples. Currently, there are no specific antiviral treatments for most onsetavirus infections, and management focuses on supportive care. Public health measures, such as hygiene and avoiding contact with potentially infected animals, are important for prevention. Further research is needed to fully understand the epidemiology, pathogenesis, and potential public health impact of onsetaviruses.