myofibroblastmediated
Myofibroblastmediated refers to processes or conditions that are caused or influenced by the activity of myofibroblasts. Myofibroblasts are specialized cells that play a crucial role in wound healing and tissue repair. They are characterized by their contractile properties, similar to smooth muscle cells, and their ability to produce extracellular matrix components, such as collagen.
The primary function of myofibroblasts is to provide mechanical force to close wounds and initiate tissue
However, persistent or excessive myofibroblast activity can lead to pathological conditions. Fibrosis, a hallmark of many
The activation and regulation of myofibroblasts are complex and involve various signaling pathways, growth factors, and