mirAO
mirAO is a novel microscopy technique that enables imaging of biological samples with unprecedented spatial and temporal resolution. Developed by researchers at the Max Planck Institute for Biophysical Chemistry, it combines principles of stimulated emission depletion (STED) microscopy with adaptive optics. The core innovation lies in the use of a wavefront sensor and a deformable mirror to correct for optical aberrations in real-time, allowing for deeper and clearer imaging within living cells and tissues.
The technique works by employing a depletion laser to confine the excitation volume to a diffraction-unlimited
mirAO has demonstrated its utility in a variety of biological applications. It has been used to observe