mikrokantajilla
Mikrokantajilla is the Finnish term for microcarrier beads used in cell culture to provide a surface for adherent cells within suspension bioreactors. Microcarriers are small spherical particles, typically 100–300 micrometers in diameter, made from materials such as polystyrene, dextran, collagen-coated glass, or agarose. Their surfaces are often chemically modified or coated with extracellular matrix proteins to promote cell attachment and spreading. In bioreactor operation, microcarriers are suspended in the culture medium under agitation, allowing cells to attach to many beads and grow in a three-dimensional, scalable culture system.
Common advantages include a high surface area-to-volume ratio, improved mass transfer and aeration compared with flat-bottom
Manufacturing and quality considerations emphasize sterility, endotoxin control, and GMP-compliant production. Bead size, surface chemistry, and
See also: microcarrier, stirred-tank bioreactor, tissue engineering.