methylfolate

Methylfolate is a form of folate, a B vitamin essential for various biological processes in the body. It is produced when folic acid, another form of folate, is methylated in the body. Methylfolate plays a crucial role in DNA synthesis, repair, and methylation, which are processes that help maintain genetic stability and regulate gene expression. It is also involved in the metabolism of homocysteine, an amino acid that, when elevated, can contribute to cardiovascular disease. Methylfolate is found in a variety of foods, including leafy greens, citrus fruits, and fortified cereals. It is also available as a dietary supplement. Deficiencies in methylfolate can lead to conditions such as megaloblastic anemia, a type of anemia characterized by large, abnormal red blood cells. Methylfolate is typically measured in micromoles per liter (µmol/L) in blood tests to assess folate status.