lääkeeluting
Lääkeeluting refers to the process of drug excretion from the body. This encompasses the elimination of a drug and its metabolites through various routes. The primary route of drug elimination is through the kidneys, a process known as renal excretion. This involves glomerular filtration, tubular secretion, and tubular reabsorption. Drugs and their metabolites are filtered from the blood in the glomeruli, then actively secreted into the renal tubules, and finally, some may be reabsorbed back into the bloodstream. The rate of renal excretion is influenced by factors such as kidney function, urine pH, and the drug's physicochemical properties.
Another significant route of elimination is hepatic metabolism, where the liver transforms drugs into more water-soluble
Other minor routes of lääkeeluting include excretion through the lungs (e.g., volatile anesthetics), sweat, saliva, and