lymphoidprimed
Lymphoidprimed is a term used in hematopoietic biology to describe a transcriptional state in early progenitor cells that shows a bias toward lymphoid lineage programs (such as B, T, and NK cells) before full lineage commitment. The concept emphasizes that certain multipotent progenitors carry an active or poised lymphoid gene expression profile, even as they retain other developmental potentials.
In mice, this idea is embodied by the lymphoid-primed multipotent progenitors (LMPP). LMPPs arise from hematopoietic
A key distinction is between LMPP (lymphoid-primed multipotent progenitors) and CLP (common lymphoid progenitors). CLPs are
Significance and scope of use vary by species and experimental context. The term is most often discussed