lipidnanopartikulid

lipidnanopartikulid are colloidal carriers composed of one or more lipid layers that encapsulate therapeutic molecules or genetic material. The core may be hydrophilic or hydrophobic, surrounded by phospholipids, cholesterol, or synthetic lipids that stabilize the particles and control their size. Surface modification with polyethylene glycol (PEG) or targeting ligands further enhances circulation time and tissue specificity. Because of their biocompatibility and ability to protect cargo from enzymatic degradation, lipidnanopartikulid are widely used in drug delivery, gene silencing, and vaccine formulations. A notable example is the messenger RNA (mRNA) vaccine technology that employs lipidnanopartikulid to deliver viral antigen sequences into cells, eliciting an immune response. The technology has also been applied to chemotherapeutic agents, enabling higher drug loading and reduced off‑target toxicity. Research continues to improve particle stability at physiological temperature, reduce immunogenicity, and expand the range of encapsulable agents. Development of pH‑sensitive or redox‑responsive lipidcomponents allows triggered release, enhancing the precision of delivery. Current clinical trials are exploring lipidnanopartikulid for the treatment of viral infections, cancers, and genetic disorders. The scalability of lipidnanopartikulid manufacturing and their regulatory profile have made them a cornerstone of modern nanomedicine.