leukemiavirus
Leukemiavirus is a non-technical, descriptive term sometimes used to denote viruses that are associated with the development of leukemia or leukemia-like diseases in animals and, more rarely, humans. Such viruses are most often members of the Retroviridae family, characterized by an RNA genome and reverse transcriptase activity, although other viral families may be involved in immune dysregulation that contributes to malignancy.
Notable examples include murine leukemia viruses (MLV), avian leukosis viruses (ALV), feline leukemia virus (FeLV), bovine
Pathogenesis commonly involves insertional mutagenesis, activation of cellular proto‑oncogenes, or expression of viral oncogenes that alter
Diagnosis relies on serology, molecular detection (PCR), and isolation of virus in culture, combined with hematologic