layersgenomics
Layersgenomics refers to an approach and, in some contexts, a software platform designed to integrate and analyze multiple layers of genomic and post-genomic data to study gene regulation and complex diseases. It focuses on creating multi-layer representations of biological systems by combining various data types to infer regulatory relationships and functional mechanisms.
Core concept and data layers encompass DNA sequence, epigenomic marks (such as methylation and histone modifications),
Technology and methods typically involve data integration techniques, graph-based and probabilistic models, and scalable pipelines that
Applications span basic research, translational science, and drug discovery. In research, layersgenomics-informed analyses aid in unraveling
Challenges include data heterogeneity and quality, missing values, standardization across laboratories, computational complexity, and the need