kortisoli

Kortisoli is a synthetic glucocorticoid medication that belongs to the corticosteroid class of drugs. It is primarily used for its anti-inflammatory and immunosuppressive properties in medical treatment.

The medication works by mimicking the effects of naturally occurring cortisol hormones produced by the adrenal glands. Kortisoli binds to glucocorticoid receptors in cells throughout the body, influencing gene expression and cellular metabolism to reduce inflammation and suppress immune system responses.

Medical applications of kortisoli include treatment of various inflammatory conditions such as arthritis, asthma, allergic reactions, and skin disorders. It is also prescribed for autoimmune diseases where the immune system attacks healthy tissues, including lupus, multiple sclerosis, and inflammatory bowel disease. The drug may be administered orally, intravenously, or through local injection depending on the condition being treated.

Common side effects of kortisoli include weight gain, fluid retention, increased blood pressure, mood changes, and elevated blood sugar levels. Long-term use can lead to more serious complications such as osteoporosis, adrenal suppression, increased infection risk, and muscle weakness. Patients taking kortisoli require careful monitoring by healthcare professionals to manage these potential adverse effects.

The medication is typically prescribed with caution in patients with certain pre-existing conditions including diabetes, hypertension, osteoporosis, and psychiatric disorders. Dosage adjustments may be necessary when kortisoli is used concurrently with other medications that affect liver metabolism or have interactions with corticosteroids.

Kortisoli should not be discontinued abruptly, as this can lead to adrenal insufficiency and withdrawal symptoms. Patients requiring long-term therapy typically follow gradual tapering schedules under medical supervision. The drug is available in various formulations including tablets, injectable solutions, and topical preparations, allowing for flexible dosing regimens based on individual patient needs and treatment responses.