jodoarenen
Jodoarenen are a class of organoiodine compounds derived from arenes in which one or more hydrogen atoms on an aromatic ring have been replaced by iodine. They include monoiodoarenes, diiodoarenes, and higher-order polyiodinated arenes. They are valued in organic synthesis for their reactivity as electrophilic substrates and as versatile leaving groups in catalytic cross-coupling reactions.
Nomenclature and structure: The parent system is benzene and its substituted derivatives. Substituents influence regioselectivity of
Preparation methods: Direct iodination uses iodine with oxidants or Lewis acids; directed iodination employs directing groups
Properties and reactivity: The carbon–iodine bond in aryl iodides is relatively weak among aryl halides, making
Applications and significance: Jodoarenes are widely used as intermediates in pharmaceutical synthesis, agrochemicals, and materials science.